Susie Wiles is the White House Chief of Staff in the second Trump administration and was the architect of the 2024 Trump campaign. In March 2026, after David Sacks's departure as White House AI czar, she took on the White House AI policy portfolio jointly with Treasury Secretary Scott Bessent.
Roles
Wiles serves as White House Chief of Staff. She managed the 2024 Trump campaign before entering the administration. Since March 2026 she has held the White House AI policy portfolio jointly with Scott Bessent, the arrangement that succeeded David Sacks's tenure as White House AI czar.
The Wiles–Bessent pairing inherited an unsettled portfolio: the Anthropic supply-chain-risk designation, the Pentagon classified-network deal that excluded Anthropic (May 1, 2026), and competing factions within the administration, including Sacks' "demystify Mythos" push and Cairncross's drafting of a frontier-AI-oversight executive order. According to reporting, Wiles's role has centered on public messaging while Bessent has been more operational on Mythos-related decisions, though the precise division of labor is not firmly established.
Positions and statements
In a late-May 6, 2026 X post, Wiles called Trump "the most forward leaning president on innovation in American history" and praised frontier labs' safety efforts. The post came as the White House was reportedly drafting a frontier-AI oversight executive order in response to Vice President JD Vance's April call with Sam Altman, Dario Amodei, Elon Musk, Sundar Pichai, and Satya Nadella over Mythos cyber-capability concerns. (Source: insideaipolicy.com)
Relationships
- related: Scott Bessent — joint AI portfolio holder.
- related: David Sacks — predecessor as White House AI lead.
- related: Sean Cairncross — National Cyber Director leading the Mythos response.
- regulator-of: Anthropic — operative White House decision-maker on Anthropic supply-chain-risk designation and Mythos federal-access posture.
- related: AI Pre-Release Vetting, EO — Trump Federal Preemption of State AI Laws (Dec 11, 2025).
Confidence
- High that Wiles is Chief of Staff and a joint AI portfolio holder.
- Medium for the precise division of labor between Wiles and Bessent on operational AI policy (public reporting has been impressionistic).